Dexamethasone is a steroid hormonal drug of the glucocorticoid class. Its main effects are anti-inflammatory and immunosuppressive. Dexamethasone can be used in different formulations: solution for injections, tablets, emulsions, eye- and eardrops and nasal spray.
Dexamethasone can be used for treatment of such diseases as rheumatic conditions (rheumatoid arthritis, systemic lupus erythematosus, scleroderma, polyarteritis nodosa, dermatomyositis etc), arthritis (podagric, psoriatic) and other acute and chronic joint diseases (osteoarthrosis, polyarthritis, ankylosing spondylitis etc), comas (hepatic, cerbral), bronchial asthma, asthmatic status, bronchospasm, acute pulmonary alveolitis, pulmonary fibrosis, sarcoidosis, berylliosis, Löffler’s syndrome, anemias, agranulocytosis, panmyelopathia, idiopathic thrombocytopenic purpura, leukaemias, myeloma, anaphylactic shock and other anaphylactoid and allergic reactions, other shocks (burn, posttraumatic, postoperative, toxic, cardiogenic, posthemotransfusional), spinal cord injury, cerebral edema of all causes, bacterial meningitis, disseminated sclerosis, Crohn’s disease, ulcerative colitis, hepatitis, acute glomerulonephritis, idiopathic nephrotic syndrome, inherent adrenal insufficiency and Addison’s disease, congenital adrenal hyperplasia in female fetus (experimentally), subacute thyroiditis, thyrotoxic crisis, dermatitis (psoriatic, contact, atopic, exfoliative, etc), exema, toxic epidermal necrolysis (Lyell’s disease), Stevens-Johnson syndrome, eyes diseases (inflammatory, allergeic, uveitis, optic neuritis, conjunctivitis of different causes, iritis etc). Besides Dexamethasone is used for altitude sickness treatment, nausea prophylaxis in a case of cytostatic therapy (antiemetic effect), to help prevent transplant rejection and lower blood calcium levels in people with bone cancers, in women at risk of preterm delivery and to prevent RDS in premature infants, and in some dental surgaries (extraction of the wisdom teeth)
Also it can be used for diagnostic purposes in a case of Cushing’s syndrome. Continue reading →