Amlodipine is a calcium channel blocker. It relaxes the arterial wall and makes it easier for blood to pass through blood vessels. The drug can be used to treat hypertension, coronary artery disease, angina pectoris (Prinzmetal’s angina and chronic stable angina pectoris), heart failure (including decompensated heart failure). It can be used as a monotherapy or in combination with other medicines.
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Usually, Amlodipine is well-tolerated by the body but about 10.8% of patients who use it can experience some side effects. The most common side effects are:
Also quite common side effects of Amlodipine include:
Like any other drug, Amlodipine can cause allergic reactions that manifest as rash (possible in the form of erythema multiforme), hives, itching, swallowing or breathing difficulty, chest tightness, swelling of the mouth, hands, eyes, face, lips, tongue and throat, unusual hoarseness, angioedema, anaphylaxis, anaphylactic shock. These reactions are serious and require immediate medical help.
In some rare cases, Amlodipine can cause such side effects as cold and clammy skin, increased appetite, loose stools, taste perversion, parosmia, gastritis, pancreatitis, dysuria, polyuria, alopecia, dermatitis, skin discoloration, skin dryness, urticarial, lichen planus, telangiectasia, bullous pemphigoid, abnormal visual `ommodation, xerophthalmia. There is a very rare case of Stevens–Johnson syndrome developing in patients who use Amlodipine.
Amlodipine can cause some changes in the laboratory tests of people using it. Therefore, you should keep in mind that Amlodipine can cause such changes in your blood tests as leukopenia, purpura, thrombocytopenia and hepatic enzyme elevations (alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase, γ-glutamyl transpeptidase, bilirubin).
All these changes are reversible after discontinuation of Amlodipine intake, and blood tests will return to normal.
Amlodipine can cause hyperglycemia especially in patients with diabetes.
Amlodipine can cause some serious side effects that may require urgent medical attention.
Such serious side effects of Amlodipine include:
There are no studies on the side effects of Amlodipine in pregnant women. Therefore, it is advisable to avoid taking this drug during pregnancy.
The side effects of Amlodipine in children are almost the same as in adults. The most common side effects in children are:
Allergic reaction in children can manifest as fever, wheezing, chest tightness, itching, cough, blue skin color, seizures, swelling of face, eyes, lips, tongue, or throat, abnormal behavior.
You may never experience any of the side effects listed above. Your doctor cannot predict your body’s reaction to Amlodipine until you have tried it. That is why you should immediately inform your doctor of any changes in your health condition after taking Amlodipine. Therefore, when you feel something is wrong, ask your doctor for advice and he or she will diagnose if your problem is connected with the medicine intake. You should also be careful because some of the side effects of Amlodipine require urgent medical attention.